tTG Elisa 96T

Introduction tTG Elisa 96T

tTG Elisa 96T

Application of tTG Elisa 96T kit

The IgA-tTg Anti kit of Arghwan Teb Kavian Company is designed for the quantitative and semi-quantitative measurement of specific antibodies of the IgA class against tTG and Gliadin antigens in human serum or plasma. This kit is supplied in a package of 96 tests by Arghvan Teb Kavian Company.

Celiac disease or celiac sprue is an autoimmune disorder of the small intestine with a genetic or hereditary background. In this digestive disease, the villi of the small intestine are damaged and the absorption of substances is disturbed. If patients with celiac disease consume a protein from the gluten group (gliadin), which is found in some grains such as wheat, barley, rye, and sometimes oats, they will experience symptoms of intolerance.

Apparently, the entry of gluten into the cells of the intestinal villi causes the immune system to respond. The inflammatory reaction created over time causes villous atrophy and reduced intestinal enzyme activity. Because most of the absorption of nutrients in the intestine is done in the intestinal villi, the destruction of the villi causes malabsorption. Most cases of celiac disease are genetic. Celiac disease is not contagious or cancerous.

This disease usually begins during infancy or early childhood (two weeks to one year old). Symptoms may appear when the child starts eating gluten-containing foods for the first time. In adults, symptoms may appear gradually over a period of months or even years.

Celiac disease is also called non-tropical spirochete and gluten-sensitive enteropathy. Celiac disease has a wide spectrum. The most common gastrointestinal symptoms include diarrhea, bloating, weight loss, steatorrhea (fatty diarrhea), bulky and colorless stools. Other symptoms of this disease include fatigue, damage to the child's growth, atrophy and muscle weakness; Malabsorption of substances such as iron and vitamin 12B.

It also causes malabsorption of calcium and vitamin D, which causes osteopenia or decreased bone density, and as a result leads to pathological bone fractures and secondary hyperparathyroidism. Other complications of the disease include amenorrhea, infertility, pyloric stenosis, ecchymosis and petechiae, vitamin K deficiency, and dermatitis herpetiformis. The prevalence of intestinal cancers is high in celiac patients.

Technical Specifications tTG Elisa 96T

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