T Uptake Elisa 192 T

Introduction T Uptake Elisa 192 T

T Uptake Elisa 192 T

Application of T Uptake Elisa 192 T kit

The uptake-T kit of Arghvan Teb Kavian Company is designed for quantitative measurement of free thyroxine hormone or 4T Free in serum or plasma. This kit is supplied in a package of 192 tests by Arghvan Teb Kavian. Two hormones thyroxine (T4) and triiodothyronine (T3) are produced by the thyroid gland and enter the blood.

Most of the T4 and T3 present in the blood are transported bound to the proteins TBG, transthyretin (formerly called prealbumin) and albumin, but the affinity of TBG to T3 is lower compared to T4, so compared to thyroxine, fraction There is more T3 in free form (0.3% of T3 compared to 0.02% of T4). The problem is due to the daily production of three times more T4 compared toT3 is the absolute value of free T4 over free T3. The biologically active part of thyroid hormones is the free part of these hormones.

Some factors such as pregnancy or the use of oral contraceptive pills cause an increase in the concentration of binding proteins of thyroid hormones, and the thyroid gland increases the production of thyroid hormones through a compensatory mechanism in these cases until the amount of free hormone is in the constant range required for the vital activities of the body. to remain In these cases, the concentration of total thyroid hormones increased, without any signs of hyperthyroidism or changes in TSH concentration.

FTI=

In this regard, Reference T-uptake is the T-uptake value of the laboratory index, which is obtained by averaging the T-uptake results of normal people. According to the T-uptake reference range, this value is often considered equal to 30 in this regard.

In hyperthyroidism and hypothyroidism, the amount of T-uptake and thyroxine increases or decreases in parallel with each other, but in abnormalities of binding proteins, the amount of these two changes in the opposite direction and following the increase of T-uptake, the amount of total thyroxine increases. decreases, or with a decrease in T-uptake, total thyroxine increases. For example, in pregnancy or taking oral contraceptive pills, an increase in the amount of total thyroxine is associated with a decrease in the amount of T-uptake.

Technical Specifications T Uptake Elisa 192 T

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