FSH Elisa 96T

Introduction FSH Elisa 96T

FSH Elisa 96T

Application of FSH Elisa 96T kit

Kit ELISA FSH of Arghvan Teb Kavian company is designed for quantitative measurement of follicle stimulating hormone or follicle stimulating hormone in serum or plasma. This kit is supplied in a package of 96 tests by Arghvan Teb Kavian Company. Follicle stimulating hormone (FSH) together with luteinizing hormone (luteinizing hormone) belong to the family of gonadotropins.

FSH and LH regulate and stimulate the growth of gonads (ovaries and testicles) synergistically. Like LH, TSH and hCG, FSH is also a glycoprotein consisting of two subunits (α and β chains) and its molecular weight is approximately 32 kilodaltons. In women, gonadotropins act in the pituitary-ovarian regulatory circuit to control the menstrual cycle. Circulating hormone levels are controlled by steroid hormones via negative feedback to the hypothalamus.

In the ovary, FSH together with LH stimulates the growth and maturation of follicles and thus the biosynthesis of estrogens in the follicles. The level of FSH shows a maximum point in the middle of the menstrual cycle, although this maximum value is less pronounced than that of LH. In the second half of the menstrual cycle or the luteal phase, especially due to the negative feedback mechanism caused by the increase in estradiol secretion, FSH secretion should gradually decrease.

Due to changes in ovarian function and decrease in estradiol secretion during menopause, we will see a significant increase in FSH during this period. In men, FSH induces spermatogenesis. Determining the concentration of FSH along with LH is used to find the cause of hypothalamus-pituitary-gonadal system dysfunction. Measurement of FSH and LH is used in cases of congenital diseases with chromosomal abnormalities, polycystic ovaries, finding the cause of menopause and menopause symptoms, distinguishing primary gonadal hypofunction from secondary hypofunction caused by pituitary hypofunction in women.

A decrease in the level of gonadotropins in men has been seen in azoospermia (decrease in the number of sperms). A correct way to evaluate ovarian function is the ovarian reserve test. A common method for this evaluation is the Clomiphene Challenge Test or CCT. During this evaluation, clomiphene is given to the patient on the fifth to ninth days of the menstrual cycle. FSH levels are expected to increase significantly around day 10, then decrease. A persistent increase in FSH indicates a decrease in ovarian reserve and a decrease in the probability of pregnancy.

Technical Specifications FSH Elisa 96T

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